Computer Aided Drug Design (CADD)

The processes of designing a new drug by using bioinformatics implements have opened a new area of drug research and development. Computational techniques assist us in searching drug target and in designing drug. Bioinformatics affects a new drug design in the following drug design path.

By using computational methods and the 3D structural information of the protein target, we are now able to scrutinise the detailed underlying molecular and atomic interactions involved in ligand:protein interactions and thus interpret experimental results in detail. The use of computers in drug discovery bears the additional advantage of delivering new drug candidates more rapidly and cost-efficiently. Computer-aided drug discovery has recently had important successes: new ligands have been predicted along with their receptor-bound structures and in several circumstances the achieved hit rates (ligands discovered per molecules tested) have been significantly greater than through experimental high-throughput screening. Strategies for CADD vary depending on the extent of structural and other information available regarding the target (enzyme/receptor) and the ligands. Computer-aided drug design (CADD) is an exciting and diverse discipline where various aspects of applied and basic research merge and stimulate each other. In the early stage of a drug discovery process, researchers may be faced with little or no structure activity relationship (SAR) information. The process by which a new drug is brought to market stage is mentioned to by a number of names most commonly as the development chain or “pipeline” and comprises of a number of distinct stages. To design a rational drug, we must firstly find out which proteins can be the drug targets in pathogenesis. In present review we reported a brief history of CADD, DNA as target, receptor theory, structure optimization, structure-based drug design, virtual high-throughput screening (vHTS), graph machines. All the world’s major pharmaceutical and biotechnology companies use computational design tools.

  • Steps Involved in CADD
  • x-ray crystallography & NMR spectroscopy
  • Bioinformatics in CADD
  • Ligand based CADD
  • Homology modelling
  • Biomarkers in medical science
  • In silico molecular design software and tools

Related Conference of Computer Aided Drug Design (CADD)

October 19-20, 2017

9th Annual Congress on Drug Design & Drug Formulation

Seoul, South Korea
October 19-20, 2017

4th International Conference and Exhibition on Pain Medicine

(10 Plenary Forums - 1 Event)
San Francisco, California, USA
October 30-November 01, 2017
A B2B Networking & Global Knowledge Exchange Forum

Annual Congress on Emerging Orphan Drugs and  Rare Diseases

San Antonio, Texas, USA
April 20-21, 2018

4th International Conference on Antibiotics: R&D, B2B

Las Vegas, Nevada, USA
April 26-27, 2018

11th European Biosimilars Congress

Rome, Italy
May 07-09, 2018

15th Annual European Pharma Congress

Frankfurt, Germany
June 18-19, 2018

9th Global Experts Meeting on Neuropharmacology

Paris, France
June 20-22, 2018

7th World Congress on Mass Spectrometry

Rome, Italy
July 09-10, 2018

12th Global
Pharmacovigilance & Clinical Trials Summit

Sydney, Australia
July 16-18, 2018

5th World Congress on Green Chemistry and Green Engineering

Melbourne, Australia
July 16-18, 2018

15th Asia-Pacific Pharma Congress

Melbourne, Australia
Jul 30-Aug 01, 2018

10th World Congress on Pharmacology

Barcelona, Spain
September 13-14, 2018

8th World Congress on Chromatography

Prague, Czech Republic
September 24-26, 2018

7th International Conference on Clinical Trials

Chicago, USA
(10 Plenary Forums - 1 Event)
October 22-23, 2018

18th Annual Pharma Middle East Congress

Abu Dhabi, UAE
September 17-18,2018

7th Global Advances in Mass Spectrometry

Singapore
November 05-06, 2018

18th Annual Pharmaceutical Chemical Analysis Congress

Madrid, Spain

Computer Aided Drug Design (CADD) Conference Speakers

Recommended Sessions

Related Journals

Are you interested in