Ibrahim Abdurrahman Adam
Northwest Normal University, China.
Title: Isolation and structural elucidation of chemical constituents, from stem bark of Xeromphis nilotica ( Rubiaceae)
Biography
Biography: Ibrahim Abdurrahman Adam
Abstract
In Africa and in many developing countries, medicinal plants are used in the treatment of various diseases and a large number of people depend on medicinal plants because they have no access to modern medicines. Xeromphis nilotica has been reported to posses bone fracture healing, antibacterial, antioxidant, anti-convulsant, anti-nociceptive and anti-inflammatory activities. Many active compounds have been reported from this plant including coumarins, alkaloids, flavonoids, terpenes saponins, Iridoids and other compounds. In the present work, on the bases of chromatographic and spectroscopic [ 1D, 2D-NMR and HR-ESI-MS ] and chemicals methods, beside four known compounds Lupeol 1, 3β-hydroxyolean-12-en-28-oic acid 2, Stigmasterol 3 and daucosterol 4, we isolated and structural elucidated new triterpenoid Saponin,3-O-{O-α-L-rhamno-pyranosyl-(1→3)-O-[-O-β-D-glucopyranosyl-(1→3)]-β-D glucopyranosyl}-Oleanolic acid 5, from stem bark of Xeromphis Nilotica.